Publication Database

Dr. Constenla's diverse body of work – encompassing peer-reviewed journals, reports, op-eds, and media publications – provides evidence-based insights to inform health policy decisions, improve health outcomes, and reduce the economic burden of infectious diseases. Collaborating closely with decision-makers at local, national, and international levels ensures her research translates into real-world impact. Explore these publications below by themes. If you would like more information about these publications, please feel free to contact us.

Hydroclimate Health Economics: Peer-Reviewed Papers

Explores the intricate link between climate, weather, and disease patterns. Learn how economic tools can guide adaptation, mitigation, and strengthen health systems against climate threats. Our research focuses on vector-borne arboviral diseases, enteric and water-related infections, malaria, and climate-oriented vaccine financing and demand forecasting. We use a comprehensive approach, including micro-costing of direct, caregiver, and productivity losses, cost-effectiveness analysis, dynamic vaccine demand modeling, and the development of sustainable financing tools.

Aedes aegypti mosquito that transmits Dengue in Brazil perched on a leaf, macro photography, selective focus

The economic impact of Aedes arboviruses and arbovirus vaccines: A review of the evidence

A review of the economic evidence of typhoid fever and typhoid conjugate vaccination and recommendations for future vaccine introduction decisions

Forecasting demand for the typhoid conjugate vaccine in low- and middle-income countries

Features of dengue and Chikungunya infections of Colombian children under 24 months of age admitted to the emergency department

Outdoor healthcare worker spraying chemical to eliminate mosquitoes in overgrown area at general location in public area

Financing dengue vaccine introduction in the Americas: Challenges and opportunities

Old abandoned tyre collected still water after rain. Condusive place for aedes mosquito breeding

Economic impact of dengue: Multicenter study across four Brazilian regions

Viral infection concept. Floating virus.

Costing dengue fever cases and outbreaks: recommendations from a costing dengue working group in the Americas

Black and white photo of a mosquito and coins

Assessing the economics of dengue: results from a systematic review of the literature

Vaccine bottles on the production line. Coronavirus vaccine has been certified and ready to injection. Many families are waiting to be vaccination from covid-19 and sars, loop 3d render.

Estimating the supply and demand of Butantan dengue vaccine In Brazil

Shot of an unrecognisable man assembling building blocks with medical icons on them

Assessing economic benefits of vaccines based on the health investment life course framework: A review of a broader approach to evaluate malaria vaccination

Biochemist of Scientist holds blood sample for Dengue Virus PCR test.

New chapter is unfolding in the fight against dengue with an unwritten ending

Expert consensus building in developing guidelines: lessons learned form a dengue economics workshop in the Americas

MALARIA mosquito sucking blood World Malaria Day Zika virus alert

The economic costs of malaria in children in three Sub-Saharan countries: Ghana, Tanzania and Kenya

Cost of diarrhea in children under 5 in Uganda

Norovirus is a gastrointestinal or intestinal virus that causes diarrhea, stomachache, and vomiting. Viral infectious diseases are spread through the air and through hand contact. 3D Rendering

Cost of diarrhea in children under 5 in Bangladesh

A Toxic Trade: The Afterlife of our Electronic Waste

Climate Change and Poverty: A Critical Connection

Exploring the Economic Impact of Climate Change: Key Insights from 2020 to 2023

Storms on the Rise: Embracing the New Reality of Hurricanes Amidst Higher Temperatures

Shielding Children from Heat Waves: A Health Priority

Climate Change’s Silent Victims: Women in Developing Countries

Population Growth and Climate Change: Navigating our Global Future

Climate Change and Birth Registration

Dengue in a Warming and Increasingly Wet World

Feeling the Burn: How Extreme Heat is Taking a Toll on our Health

Our publications provide data-driven insights for making informed health investment decisions. We utilize economic evaluations, where we compare the value of different interventions through cost-effectiveness, cost-utility, cost-benefit, and budget impact analyses. We also use investment analyses to assess the potential returns and risks associated with various health programs and initiatives. Explore the database to find research that can help you maximize the impact of your health investments.

15-year experience with rotavirus vaccination in Mexico: A systematic literature review

Question What If Handwritten With Black Marker

Contingent Valuation: A pilot study for eliciting willingness to pay for a reduction in mortality from vaccine-preventable illnesses for children and adults in Bangladesh

Budget impact analysis of pneumococcal conjugate vaccines in Colombia

Costs of immunization programs for 10 vaccines in 94 low- and middle-income countries from 2011-2030

African-American man signs papers that doctor gives him before getting vaccine at the hospital

Return on Investment from Immunization Programs Against 10 Pathogens in 94 Low- and Middle-Income Countries from 2011-2030

Striped mosquitoes are eating blood on human skin. Mosquitoes are carriers of dengue fever and malaria.Dengue fever is very widespread during the rainy season.

The economic impact of Aedes arboviruses and arbovirus vaccines: A review of the evidence

Scoping review of investment cases for vaccines and immunization programs

financial graphs and charts isolated on white

Estimating the value of pneumococcal conjugate, haemophilus influenzae type b and rotavirus vaccination in India

A review of the economic evidence of typhoid fever and typhoid conjugate vaccination and recommendations for future vaccine introduction decisions

Forecasting demand for the typhoid conjugate vaccine in low- and middle-income countries

Money savings, investment, making money for future, financial wealth management concept.

Poverty reduction and equity benefits from the introduction or scaling up of measles, rotavirus and pneumococcal vaccines in low- and middle-income countries: findings from a modeling study

IMPACT Concept. Chart with keywords and icons on white background

The equity impact vaccines may have on averting deaths and medical impoverishment in developing countries

Human Papilloma Virus vaccine with syringe and vial

Geospatial planning and the resulting economic impact of Human Papillomavirus Vaccine introduction in Mozambique

Decision-Tree Model for Support of Health Policy Choices Based on Pneumococcal Conjugate Vaccine (PCV) Program Outcomes

TETANUS TOXOID text meaning explanation vaccination

The economic value of increasing geospatial access to tetanus toxoid immunization in Mozambique

Needle of a disposable syringe with a drop of liquid on the tip against the background of a fragment of a US dollar bill

Financing dengue vaccine introduction in the Americas: Challenges and opportunities

Human Crowd Surrounding An Injectable Pneumococcal Vaccine Bottle On Purple Background

Exploring variation in cost-effectiveness estimates in studies that evaluate adult pneumococcal vaccination in Latin America

Assessment and analysis by professional auditing consultant concept, person touching screen with icons of risk evaluation, business analytics, quality compliance, process inspection, financial audit

Post-introduction economic evaluation of pneumococcal conjugate vaccination in Ecuador, Honduras and Paraguay

Economic impact of meningococcal outbreaks in Brazil and Colombia

Aedes mosquitoe is sucking blood on human skin

Economic impact of dengue: multicenter study across four Brazilian regions

Costing dengue fever cases and outbreaks: recommendations from a costing dengue working group in the Americas

Aedes aegypti or yellow fever mosquito sucking blood on skin,Macro close up show markings on its legs and a marking in the form of a lyre on the upper surface of its thorax

Assessing the economics of dengue: results from a systematic review of the literature

Estimating the supply and demand of Butantan dengue vaccine In Brazil

Assessing economic benefits of vaccines based on the health investment life course framework: A review of a broader approach to evaluate malaria vaccination

Is the world ready for an Ebola vaccine?

Red and white blood cells move inside the artery. Red blood cells carry nutrients for the whole body, for example, oxygen. Medical science illustration

Cost-effectiveness of a quality improvement programme to reduce central line associated bloodstream infections in intensive care units in the USA

Estimating the costs associated with a community outbreak of meningococcal disease in a Colombian Caribbean City

Vaccine vials with syringe and euro bills.

Reassessing the value of vaccines

Quality control certification, checked garantee of standard

Expert consensus building in developing guidelines: Lessons learned form a dengue economics workshop in the Americas

The economic costs of malaria in children in three Sub-Saharan countries: Ghana, Tanzania and Kenya

Coronavirus vaccine vials in hospital with money

Identifying unit costs for use in regional economic evaluation: An example of an economic analysis of childhood pneumococcal conjugate vaccine in Latin America and the Caribbean

Arrow Symbols And Seesaw Balance Scale Concept

Estimating the cost-effectiveness of pneumococcal conjugate vaccination in Brazil

Economic impact of a rotavirus vaccination program in Mexico

Rotavirus, contagious reoviridae RNA virus, agent of diarrhea disease, gastroenteritis, fever, stomach flu infection

Economic impact of a rotavirus vaccine in Brazil

Streptococcus Pneumoniae Bacteria in Lungs

The cost-effectiveness of pneumococcal conjugate vaccine in Latin American and the Caribbean: A regional analysis

Hand shows a model energy efficient house.

Economic impact of pneumococcal conjugate vaccination in Brazil, Chile, and Uruguay

Potential cost-effectiveness of vaccination for rotavirus gastroenteritis in Latin America

Cost-effectiveness analysis of rotavirus vaccine in Chile

Vaccine Production Facility. Medication Manufacturing Process. Glass Vials with Orange Caps on Conveyor Belt. Medical Ampoule Production Line at Modern Pharmaceutical Factory.

Economic impact and cost-effectiveness analysis of rotavirus vaccine in Venezuela

Business perfomance review or KPI key point indicator estimation concept, calculator with magnifier glass on pile of graph and chart performance print paper on wood table

Use of various methods for cost estimation in multi-national economic evaluations

Scales with a stack of different pills and money euro banknotes and coins. Concept of healthcare costs, rising prices of medicines and nutritional supplements. Financial crisis in medicine

The value of medicines: is there enough economic evidence?

We have extensive expertise in quantifying the economic burden of disease in low- and middle-income countries, serving as a vital resource for shaping effective healthcare policy. Our systematic approach provides reliable results through rigorous, standardized data collection and analysis, cross-regional insights, and comparative analyses of disease prevalence and costs across multiple regions. We also offer actionable guidance with clear recommendations for resource allocation, policy development, and intervention strategies.

The economic burden of pneumonia in children under five in Uganda

Measles disease. Health concept, Infectious, viral diseases. Vaccination of children against measles. close up

The economic burden of measles in children under five in Bangladesh

The economic burden of measles in children under five in Uganda

Question What If Handwritten On Sticky Note

Contingent Valuation: A pilot study for eliciting willingness to pay for a reduction in mortality from vaccine-preventable illnesses for children and adults in Bangladesh

Close-Up Portrait Of Boy Looking Away At Home

The cost of eight pediatric infectious illnesses in low- and middle-income countries: A systematic review of cost of illness studies.

Female Doctor hand holding syringe and covid-19 vaccine in blue gloves with white coat. Disease injection concept, close-up image. Vaccine.This is futuristic, virtual reality, hologram, and technology concept.

Costs of immunization programs for 10 vaccines in 94 low- and middle-income countries from 2011-2030

Estimating the costs of invasive pneumococcal disease in older children and adults in selected countries of Latin America

Brain viral infection, Viral meningitis and encephalitis. 3d illustration

Estimating the opportunity costs of treating meningitis in selected countries of Latin America

Costing dengue fever cases and outbreaks: recommendations from a costing dengue working group in the Americas

Connected People - Social Media, Networking - Coronavirus, Epidemiology, Infectious Disease

Estimating the costs associated with a community outbreak of meningococcal disease in a Colombian Caribbean City

The economic costs of malaria in children in three Sub-Saharan countries: Ghana, Tanzania and Kenya

Wooden seesaw scale empty on wooden sphere on wood table with wording VALUE and PRICE balancing

Identifying unit costs for use in regional economic evaluation: An example of an economic analysis of childhood pneumococcal conjugate vaccine in Latin America and the Caribbean

Evaluating the costs of pneumococcal disease in selected Latin American countries

Economic and health burden of rotavirus gastroenteritis in eight Latin American and Caribbean countries

Use of various methods for cost estimation in multi-national economic evaluations

European currency with doctor stethoscope.

Understanding the costs of Pneumonia, Diarrhea, and Measles in Uganda - The Decade of Vaccine Economics study reveals significant household costs associated with childhood diseases

Life balance choices signpost, with sunrise sky backgrounds

Pneumonia, diarrhea and measles force Bangladeshi households to make difficult financial decision when illness arise

Payment for medical services. Medical health care billing statement in hospital, top view

DOVE-IV: Measuring the cost of illness

Pig piggy bank and medical equipment such as stethoscope lined up on the desk

Measuring the cost of childhood diseases – laying the groundwork for countries in Asia to establish a viable plan for standardized data collection, data entry and data monitoring procedures

Understanding the financial toll of childhood illness

Healthcare business graph data and growth, Doctor use calculator and calculate healthcare costs and analyzing medical report on tablet.

What is the financial toll of common childhood illness?

The potential economic impact of the Zika virus

Costing dengue cases and outbreaks: A guide to current Practices and Procedures

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Publication Database

Hydroclimate Health Economics: Peer-Reviewed Papers

Hydroclimate Health Economics: Op-Eds and Media Publications

Economic Evaluations and Investment Analysis

Disease Burden and Cost-of-Illness Studies: Peer-Reviewed Papers

Disease Burden and Cost-of-Illness Studies: Op-Eds and Media Publications